Medicinal Chemistry Research Open Access

 Medicinal Chemistry is that the science that deals with the invention or style of latest therapeutic chemicals and their development into helpful medicines. it's going to involve synthesis of latest compounds, investigations of their relationships between the structure of natural or artificial compounds and their biological activities, elucidations of their interactions with receptors of varied types, together with enzymes and deoxyribonucleic acid, the determination of their absorption, transport, and distribution properties, and studies of the metabolic transformations of those chemicals into different chemicals   Medicinal chemistry, in its crudest sense, has been practiced for many thousand years. Man has looked for cures of sicknesses by mastication herbs, berries roots, and barks. a number of these early clinical trials were quite triple-crown, however, not till the last a hundred year has information of the active constituents of those natural sources been acknowledged. The earliest written records of the Chinese, Indian, South yank, and Mediterranean cultures delineate the therapeutic effects of varied plant concoctions. If the approach to drug discovery continued as in history, few diseases would be treatable these days. Natural merchandise form up atiny low share of medicine on the present market. Typically, once a natural product is found to move, it's with chemicals changed so as to boost its properties. As a results of advances created in synthesis and separation strategies and organic chemistry techniques since the late Nineteen Forties, a additional rational approach to drug discovery has been potential, namely, one that involves the component of style.