Immunomics
Immunomics is the study of
immune system regulation and response to pathogens using genome-wide approaches. With the rise of genomic and
proteomic technologies, scientists have been able to visualize biological networks and infer interrelationships between genes and/or proteins; recently, these technologies have been used to help better understand how the
immune system functions and how it is regulated. Two thirds of the
genome is active in one or more immune cell types and less than 1% of genes are uniquely expressed in a given type of cell. Therefore, it is critical that the expression patterns of these immune cell types be deciphered in the context of a network, and not as an individual, so that their roles be correctly characterized and related to one another. Defects of the
immune system such as autoimmune diseases, immunodeficiency, and malignancies can benefit from genomic insights on pathological processes. For example, analyzing the systematic variation of
gene expression can relate these patterns with specific diseases and
gene networks important for immune functions.
Immunomics studies the response and regulation process of the
immune system on pathogens, which deals with all immune-related molecules, together with their targets and functions.
Immunomics includes the techniques of genomics,
proteomics, and bioinformatics
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