ISSN: 1755-5191

Imaging in Medicine

Salivary Diagnostics

 Salivary diagnostics plays an vital role in the early discovery and deterrence of many oral and systemic diseases in a fast and noninvasive way. Saliva collection is an easy, repeatable and inexpensive diagnostic cause that can be used for both diagnosis and real-time observing of various human diseases. In the near future, many industrialized and validated salivary biomarkers have the latent to reach the clinical practice. Five diagnostic constituents of saliva include proteomics, transcriptomics, metabolomics, macrobiotics and microRNAs. Based on them, the afresh emerging technologies of salivary diagnostics are developed that include RNA-sequencing, point-of-care technologies and liquid biopsy. They have potential to allow screening, early detection, prognosis and monitoring of various human diseases. The recent developments extended the salivary diagnostic approach from the oral cavity to the whole physiological system, thus toward personalized individual medicine applications.  

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