Journal of Biochemistry Research

Oxidative Stress Open Access Articles

 Oxidative stress is basically AN imbalance between the assembly of free radicals and also the ability of the body to counteract or detoxify their harmful effects through neutralization by antioxidants. A free radicals is AN element containing molecule that has one or a lot of mismatched electrons, creating it extremely reactive with alternative molecules.Oxygen by-products area unit comparatively unreactive however a number of these will endure metabolism inside the biological system to offer rise to those extremely reactive oxidants. Not all reactive element species area unit harmful to the body. a number of them area unit helpful in killing offensive pathogens or microbes.However, free radicals will with chemicals act with cell parts like deoxyribonucleic acid, macromolecule or supermolecule and steal their electrons so as to become stabilised. This, in turn, destabilizes the cell element molecules that then ask for ANd steal an lepton from another molecule, thus triggering an oversized chain of radical reactions. each cell that utilizes enzymes and element to perform functions is exposed to element radical reactions that have the potential to cause serious injury to the cell. Antioxidants area unit molecules gift in cells that stop these reactions by donating AN lepton to the free radicals while not turning into destabilized themselves. AN imbalance between oxidants and antioxidants is that the underlying basis of aerophilic stress. aerophilic stress results in several pathophysiological conditions within the body. a number of these embrace neurodegenerative diseases like shaking palsy and Alzheimers, cistron mutations and cancers, chronic fatigue syndrome, fragile X syndrome, heart and vas disorders, induration of the arteries, heart disease, attack and inflammatory diseases.  

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