Neuroscience and Psychiatry: Open Access

High Impact Factor Journals In Proteomics

 Proteomics is the large-scale study of proteomes. A proteome may be a set of proteins produced in an organism, system, or biological context. We may ask, as an example , the proteome of a species (for example, Homo sapiens) or an organ (for example, the liver). The proteome isn't constant; it differs from cell to cell and changes over time. To a point , the proteome reflects the underlying transcriptome. However, protein activity (often assessed by the reaction rate of the processes during which the protein is involved) is additionally modulated by many factors additionally to the expression level of the relevant gene.   Proteomics is used to investigate   ·       when and where proteins are expressed ·       rates of protein production, degradation, and steady-state abundance; ·       how proteins are modified (for example, post-translational modifications (PTMs) such as phosphorylation); ·       the movement of proteins between subcellular compartments ·       the involvement of proteins in metabolic pathways; ·       How proteins interact with one another.   ·       Proteomics can provide significant biological information for several biological problems, such as: ·       Which proteins interact with a particular protein of interest (for example, the tumour suppressor protein (Human example) ·       Which proteins are localised to a subcellular compartment (for example, the mitochondrion)? (Human example) ·       Which proteins are involved during an organic process (for example, circadian rhythm)? (Human example)

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