Hereditary Angiodema Top Open Access Journals

Hereditary angioedema is a disorder characterized by recurrent  of severe swelling . The most common areas of the body to develop swelling are the limbs, face, intestinal tract, and airway. Minor trauma or  may trigger an attack, but swelling often occurs without a known trigger. Episodes involving the intestinal tract cause severe abdominal pain, nausea, and vomiting. Swelling in the airway can restrict breathing and lead to life-threatening of the airway.  Where you have it on your body, how often the bouts happen, and how strong they are different for everyone. The attacks can come and go as well as move to different spots during the same bout. The swelling typically goes away on its own but can also occur as a life-threatening event. Your throat can swell. That can cut off your airways and could be deadly. So if you know you have HAE and you feel any change like that, call 911 right away. The frequency of attacks can vary. You can have attacks as often as every 1 to 2 weeks or 1 to 2 per year, and they can be hard to manage. Causes A problem with a gene that makes a blood protein called C1 inhibitor often causes HAE. In most cases, you don’t have enough of this protein. In others, you have normal levels but it doesn't work right. For the most common form of HAE, if one of your parents has HAE, you have a 50% change of having it, too. But sometimes the gene change happens for unknown reasons. If you have the broken gene, you can pass it on to your children.

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