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Hepatic Steatosis,liver Weight,intrahepatic Fat,triacylglycerols,hepatoprotective,metabolic Failure,non-alcoholic Fatty Liver Disease,type 2 Diabetes,dyslipidemia,intrahepatic,β-oxidation,lipoprotein Secretion, Fatty Li

Hepatic Steatosis Scholarly journal: Hepatic steatosis is defined as at least 5 per cent of liver weight intrahepatic fat. Simple deposition of triacylglycerols in the liver can be hepatoprotective; however, excessive storing of lipid can result in liver metabolic failure, inflammation, and advanced types of non-alcoholic fatty liver disease. Obesity, type 2 diabetes, and dyslipidemia are associated with nonalcoholic hepatic steatosis. The deposition of intrahepatic fat includes many pathways, including enhanced transport of fatty acids to the liver, decreased de novo lipogenesis and/or reduced clearance by β-oxidation or very low-density lipoprotein secretion. Hepatic steatosis is referred to as fatty liver that is caused by excessive accumulation of triglycerides and other fat types. The major cause of hepatic steatosis is high-volume alcohol intake that directly influences the liver cells. Type 2 diabetes, insulin tolerance and elevated cholesterol are other contributing factors for developing fatty liver. Steatosis is more frequent in women, and can also occur in smaller amounts in low-intake lean individuals. Both hepatic steatosis although steatohepatitis, and they do not induce any signs in early phases (they are asymptomatic) and are typically diagnosed indirectly by ultrasound or CT scans. Actually, the situation is not painful, and for a long time it may remain unnoticed. In severe cases, the liver can grow to more than three times its normal size, and may be painful and tender.

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