Genometyping Online Journals
Genome typing is the process of evaluating the differences in the genetic make-up of an individual by examining the individual's DNA sequence using biological assays and comparing it to another individual's sequence or a reference sequence. It involves study of an individual's inheritence.It is the use of DNA sequences to evaluate biological populations by use of molecular tools. The success of
personalized medicine rests on understanding the genetic variation between individuals. Thus, as medical practice evolves and variation among individuals becomes a fundamental aspect of clinical medicine, a thorough consideration of the genetic and genomic
information concerning the animals used as models in biomedical research also becomes critical. In particular, nonhuman primates (NHPs) offer great promise as models for many aspects of human
health and disease. These are outbred
species exhibiting substantial levels of genetic variation; however, understanding of the contribution of this variation to phenotypes is lagging behind in NHP species. Thus, there is a pivotal need to address this gap and define strategies for characterizing both genomic content and variability within
primate models of human disease. Here, we discuss the current state of
genomics of NHP models and offer guidelines for future work to ensure continued improvement and utility of this line of biomedical research.
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