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 The early lactation period of dairy cows is normally categorized by a status of negative energy balance because the ingestion of nutrients and energy are inadequate to meet the high energy demands of milk production. The consequential hypoglycemia causes mobilization of fat and muscle reserves and synthesis of ketone bodies in the liver, leading to ketosis and metabolic acidosis. Furthermore, oxidative stress rises and the immune function is hampered Subclinical ketosis is a severe problem in dairy farms since it affects nearly 40% of cows in a herd although the incidence could be higher. Proteomics has helped to understand this syndrome: plasma proteomics showed that ketosis is associated to inflammation, since it revealed an increase in APP, complement and coagulation pathways, and an increase of antioxidant GPx as compensatory mechanisms.   The main objective was to judge the potential of grass silages of terribly top quality to support a high milk yield with an occasional or moderate, or perhaps while not concentrate supplementation. Production responses to exaggerated levels of concentrate supplementation with three primary growth grass silages differing in edibleness were studied mistreatment sixty six Norwegian Red dairy farm cows. Crops were chop-chop limp (<24h) and a formic acid-based additive was applied. All silages were restrictedly soured. ensilage digested organic matter in dry matter (DM) values were 747, 708, and 647 g/kg of DM for H1, H2, and H3, severally.    

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