Annals of Clinical Trials and Vaccines Research

Cell-mediated Immunity

 Cell-mediated immunity is an immune response that does not involve antibodies, but rather involves phagocyte activation, antigen-specific cytotoxic T-lymphocytes, and the problem of various cytokines in response to an antigen. Cellular immunity protects the body by: triggering antigen-specific T-lymphocytes capable of inducing apoptosis in body cells with foreign antigen epitopes on their surface, such as cells with intracellular pathogens, virus-infected cells and cancer cells with tumor antigens; triggering macrophages and natural killer cells to destroy pathogens; Cell-mediated immunity is mainly administered to microbes surviving in phagocytes and microbes contaminating non-phagocytic units. This is also the most effective way to kill virus-infected cells, but it also serves to protect against intracellular bacteria, protozoa, fungi and cancers.  

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