Journal of Biochemistry Research

Animal Proteomics

 Animal proteomics is an evolving field which holds an excellent promise not just for fundamental and applied discoveries regarding biology and pathology of domestic species, but also can be implemented in comparative applications of human diseases research. Animal proteomics is a field of study in its own right with application to the biology and pathology of domestic species providing valuable insight in fundamental aspects of every species. Animal studies are an important component of each field of medical and basic scientific research a minimum of for the last 150 years. Various animals like rats, mice, dogs, cats, rabbits, fishes, birds (mainly chicken), pigs, cows, and primates are being used in research. domestic animals offer advantages for research in proteomics in experimental design, sample selection, and sample preparation due to the possibility to adapt to the environment and therefore the broad availability of diverse biological samples including biofluids (urine, serum/plasma, milk, saliva, sperm), cells, and tissues. The increased availability of species‐specific antibodies, commercially available combinatorial peptide libraries, and library display technologies, essential for the low‐abundance proteome enrichment and therefore the isolation of specific high‐affinity binding molecules is facilitating the depletion of abundant proteins and validation of candidate protein biomarkers from any animal species.  

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