Toxicokinetics Journals

The epithelial barriers that form the body’s interface with the environment, and the cellular barriers that separate internal organs and tissues, have to be permeable to a wide variety of chemicals to allow nutrient absorption and waste product elimination. Toxicokinetics is the study of the time course for toxicants in terms of synthesis, absorption and excretion. Toxicokinetic analysis is the toxin activity characterisation process. The study addresses the overall processes that the toxin undergoes upon entering the body, or otherwise how the body treats the toxin. Toxicokinetics (often abbreviated as 'TK') describes both the rate at which a chemical enters the body and what happens to excrete and metabolize the compound once it is inside the body.It is an application of pharmacokinetics to determine the relationship between the systemic exposure of a compound and its toxicity.