Journal of Pediatric Neurological Disorders

Subthalamic Nucleus

In terms of anatomy, the subthalamic nucleus is the greater component of the subthalamus. This is a small nucleus in the brain, formed in the lens. The subthalamic nucleus, as suggested by its name, lies ventral to the thalamus. It develops, embryologically, from the lateral column of hypothalamic cells. The STN receives from the frontal cortex an exciting, glutamatergic input with large contributions from motor areas including the primary motor cortex, premotor and supplementary motor cortex, and frontal eye fields.As the basal ganglia 's complex roles have been increasingly studied in recent decades, knowledge of the role of the subthalamic nucleus (STN) in motor and cognitive roles has developed.

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