Protein Calorie Malnutrition Open Access Articles:
Alteration in endocrine levels because of PCM may also cause fluid retention. Plasma levels of mineralocorticoid area unit raised in
malnutrition however they're not altered in malnutrition. This successively ends up in Na retention at the extent of excretory organ tubules, rise in Pitressin (ADH) secretion, water retardation and dropsy resulting in malnutrition. The plasma corticoid levels area unit raised to a larger extent in
malnutrition than in malnutrition. Raised corticoid levels cause breakdown of muscle super molecule and therefore the discharged amino acids area unit amused to liver for synthesis of plasma proteins. Somatomedin activity is reduced in
malnutrition however not just in case of malnutrition. Low levels of both plasma amino acids somatomedins are also operative as a feedback stimulating pituitary to secrete augmented quantities of hormone. Plasma
hormone levels area unit raised in
malnutrition and their lypolytic action offers rise to high levels of plasma free fatty acids. Fats accumulate within the liver because of reduced synthesis of compound protein and impaired viscus perform offers rise to
organic chemistry changes and dropsy characteristics of malnutrition.
Clinical signs and symptoms of protein-energy deficiency disease (PEM) embrace the following:
• Poor weight gain.
• Slowing of linear growth.
• Behavioral changes - Irritability, apathy, weakened social responsiveness, anxiety, and a focus deficit.
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