Annals of Clinical Trials and Vaccines Research

Pharmacogenomics Open Access Articles

 Pharmacogenomics is the study of genome's role in responding to drug research. The name  reflects as a combination of pharmacology and genomics. Pharmacogenomics analyzes how an individual's genetic makeup affects his / her reaction to drugs. The term pharmacogenomics is also used with pharmacogenetics, interchangeably. While both terms relate to genetic influences-based drug response, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics embraces a more genome-wide association approach, incorporating genomics and epigenetics while addressing the effects of multiple genes on drug response. Pharmacogenomics Improve the safety of drugs and reduce ADRs;Tailoring treatments to meet the unique genetic predisposition of patients, identifying optimal dosing; improving the discovery of drugs targeted at human disease; and improving evidence of principle for efficacy studies. Pharmacogenomics can be applied to numerous medical areas, including pain management, cardiology, oncology, and psychiatry. There may also be a place in forensic pathology where pharmacogenomics can be used to determine the cause of death in drug-related deaths where autopsy results in no findings.

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