Annals of Clinical Trials and Vaccines Research

New Journals In Pharmacoepidemiology

Pharmacoepidemiologal studies is to broaden the knowledge and science underlying post-marketing drug surveillance (studies conducted after a medicine has been released into the market) and disease surveillance. And Bridge the gap between the information generated by pre-marketing clinical trials and the real world drug usage. Effectiveness and safety of drugs are thoroughly studied in randomised clinical trials. However, few data are available on these parameters in everyday clinical practice. The effectiveness and utilisation of drugs may be different than expected as daily practice differs from the experimental setting with respect to the heterogeneity of patients, their age, treatments and co-morbidity. Moreover, important safety issues may not be detectable in clinical trials because the frequency of many adverse events is low and adverse effects may occur many years after drug administration (van Herk, Pharmacoepi Drug Saf 2012). Disease surveillance studies are used to create insight in the presence of the disease in a population-based sample. Pharmacoepidemiology studies quantify drug use patterns and adverse drug effects.5 For example, they are interested in understanding the patterns of drug prescribing, the appropriateness of use, medication adherence and persistence patterns, and the identification of predictors for medication use. Pharmacoepidemiologists also conduct safety studies of drug use in large populations. They are interested in common, predictable adverse drug reactions as well as the uncommon and unpredictable ones. It is important to note a few terms that are often used when discussing drug safety.    

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