Mycobacterium Bovis Genome

 Mycobacterium bovis is the causal agent of tuberculosis in a variety of creature species and man, with worldwide yearly losses to farming of $3 billion. The human weight of tuberculosis caused by the bovine tubercle bacillus is still mainly unknown. M. bovis was also the progenitor for the M. bovis bacillus Calmette–Guérin vaccine damage, the most broadly used human vaccine. Here we describe the 4,345,492-bp genome series of M. bovis AF2122/97 and its contrast with the genomes of Mycobacterium tuberculosis and Mycobacterium leprae. Noticeably, the genome series of M. bovis is >99.95% identical to that of M. tuberculosis, but elimination of genetic information has led to a concentrated genome size. Comparison with M. leprae reveals a number of common gene dead, suggesting the taking away of functional redundancy.