McCune-Albright Syndrome, Gene, Tumor, Endocrine

 McCune-Albright syndrome is a rare, genetic, non-hereditary disease that causes bone tumors, bone deformities and fractures. Manifestations of SAM in each individual depend on the extent and distribution of the abnormal cells. Abnormal and prolonged activation of multiple peripheral endocrine glands occurs even though the necessary stimulating pituitary hormones may be absent. Early puberty, with the start of breast development, pubic hair and the start of menstruation from the first months of life in women.  

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