Journal of Biochemistry Research

Lipidomics Uses

Lipidomics is a newly emerging discipline that studies large-scale, cellular lipids based on principles of analytical chemistry and technological tools , especially mass spectrometry. Recently, techniques have evolved considerably, and novel applications of lipidomics have emerged in the biomedical sciences. Lipids play an integral part in human physiology and exhibit a high degree of specialization in specific cellular compartments, functioning as structural components of membranes, as a storage medium for energy, as an anchor for proteins, as intracellular and intercellular signaling molecules, or as cofactors in the modulation of protein activities. Deficiencies or alterations in lipid enzymatic metabolism may lead to common disease pathogenesis, such as Alzheimer's disease, atherosclerosis, insulin-resistant diabetes, cancer, or schizophrenia. Lipid biomarkers therefore have potential applications to understand the mechanisms underlying pathogenesis of diseases 

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