Journals List Of Lipidomics
Lipidomics is that the large-scale study of pathways and networks of cellular lipids in biological systems. The word "lipidome" is employed to explain the entire lipid profile within a cell, tissue, organism, or
ecosystem and may be a subset of the "metabolome". This rapidly expanding field complements the large progress made in
genomics and
proteomics, all of which constitute the family of systems biology. Lipids play an integral part in human
physiology and exhibit a high degree of specialization in specific cellular compartments, functioning as structural components of membranes, as a medium for energystorage, as an anchor for
proteins, as intra- and inter-cellular
signalling molecules or as cofactors in modulating protein activity. A multitude of nutritionally and metabolically regulated processes maintain lipid
homeostasis in healthy conditions. Defects or alterations in the enzymatic metabolism of lipids may contribute to the
pathogenesis of common diseases, like Alzheimer’s disease , atherosclerosis, insulin-resistant
diabetes ,
cancer or schizophrenia. Thus, lipid
biomarkers have potential applications in the
understanding of mechanisms underlying disease pathogenesis, in the prediction of future disease risk and in monitoring the responses to therapies. Lipid researchers refer to the entire collection of chemically distinct lipid
species in a cell, an organ, or a biological system as a “lipidome”.
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