Research on Chronic Diseases

Innate Immunity Online Journals

By contact, ingestion, and inhalation, humans are exposed to millions of potential pathogens per day. Our ability to avoid infection depends in part on the adaptive immune system, which recalls previous encounters with specific pathogens and destroys them once again when they attack. However, on first exposure to a new pathogen, adaptive immune responses are slow to develop, as specific clones of B and T cells need to be activated and expanded; therefore, it may take about a week before the responses become effective. By contrast, a single bacterium with a one hour doubling time can produce nearly 20 million progeny in a single day, a full-blown infection. Therefore we rely on our innate immune system during the first critical hours and days of exposure to a new pathogen to protect us from infection. Innate immunity online journals provides a wide range if articles on innate immunity.

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