Neuroscience and Psychiatry: Open Access

Heroin Addiction Scientific Journals

 HeroinAddiction may be a encephalopathy define by passionate engagement in rewarding stimuli despite adverse consequences. Despite the involvement of variety of psychosocial factors, a biological process—one that's induced by repeated exposure to an addictive stimulus—is the core pathology that drives the development and maintenance of an addiction, according to the "brain disease model" of addiction. Addiction is a disorder of the brain’s reward system which arises through epigenetic mechanisms and establishes over time from chronically high levels of exposure to an addictive stimulus .A critical component and customary factor in the development of virtually all forms of behavioral and drug addictions. Addiction exacts an "astoundingly high financial and human toll" on individuals and society as a whole. Classic hallmarks of addiction include impaired control over substances or behavior, preoccupation with substance or behavior, and continued use despite consequences. There are a number of genetic and environmental risk factors for developing an addiction, that vary across the population. Genetic and environmental risk factors each account for roughly half of an individual's risk for developing an addiction. Even in individuals with a relatively low genetic risk, exposure to sufficiently high doses of an addictive drug for a long period of time. Overall, the data implicating specific genes in the development of drug addiction is mixed for most genes. One reason for this might be that the case is thanks to attention of current research on common variants.  

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