Genetic Diseases Open Access Journals

 A genetic disorder is a health condition which is caused by one or more genome abnormalities.It May be caused by a single (monogenic) or multiple (polygenic) gene mutation  Though the most common polygenic disorders are, the word is Used mainly when addressing particular genetic cause conditions, either in a gene or Gene-Chromosome. The responsible mutation can occur spontaneously before being embryonic development (a de novo mutation), or it can be inherited from two parents who are carriers of a Deficient gene (autosomal recessive inheritance) or the disordered parent (autosomal) dominant inheritance). Some disorders are caused by a mutation on the X chromosome and have X-linked inheritance. The Y chromosome is inherited in very few diseases or mitochondrial DNA.Researchers are learning that nearly all conditions and diseases have a genetic component. Some diseases, including sickle cell disease and mucous fibrosis, are caused by mutations in a single gene.Three types of genetic disorders: 1.Single-gene disorders, where a mutation affects one gene. Sickle cell anemia is an example2.Chromosomal disorders, where chromosomes (or parts of chromosomes) are missing or changed.3.Complex disorders, where there are mutations in two or more genes.  

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