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The lipidome refers to the totality of lipids in cells. Lipids are one among the four major molecular components of biological organisms, along side proteins, sugars and nucleic acids. Lipidome may be a term coined within the context of omics in modern biology, within the sector of lipidomics. It are often studied using mass spectrometry and bioinformatics also as traditional lab-based methods.The lipidome of a cell are often subdivided into the membrane-lipidome and mediator-lipidome. Lipidomics is that the large-scale study of pathways and networks of cellular lipids in biological systems. The word "lipidome" is employed to explain the entire lipid profile within a cell, tissue, organism, or ecosystem and may be a subset of the "metabolome" which also includes the three other major classes of biological molecules: proteins/amino-acids, sugars and nucleic acids. Lipidomics may be a relatively recent research field that has been driven by rapid advances in technologies like mass spectrometry (MS), nuclear resonance (NMR) spectroscopy, fluorescence spectroscopy, dual polarisation interferometry and computational methods, including the popularity of the role of lipids in many metabolic diseases like obesity, atherosclerosis, stroke, hypertension and diabetes. This rapidly expanding field complements the large progress made in genomics and proteomics, all of which constitute the family of systems biology.          

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