Bioavailability Scholarly Peer-review Journal
Bioavailability is a subcategory of absorption in pharmacology, and is the fraction (percent) of a given drug that reaches systemic circulation. Bioavailability of a drug is an average value; in order to take into account population variability, deviation range is given in ±. To ensure sufficient dosage of the drug-taker with poor absorption, the lower value of the deviation range is used to reflect actual bioavailability to measure the drug dose needed by the drug-taker in order to achieve systemic drug concentrations comparable to the intravenous one. Regarding dietary supplements, herbs and other nutrients in which the route of
administration is almost always oral, bioavailability usually simply indicates the quantity or fraction of the absorbed dose. Bioavailability is calculated in both
pharmacology and
nutrition sciences by measuring the region under curve (AUC) of the time profile for concentration of the drug.
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