Review Articles For Drug Discovery
In recent years drug discovery science has evolved into a distinct branch of science. It is highly multidisciplinary including among others, the disciplines of chemistry, multiple branches of biology (from molecular to behavioral biology), biophysics, computer sciences, mathematics and engineering. It distinguishes itself from academic biomedical sciences by having as its goal and measure of success a pharmacological therapy, while the focus of the academic
environment is the generation of new knowledge. Scientists in a drug discovery
environment must, therefore, be able to work in multidisciplinary teams, often not of their choosing, and must be able to communicate their specialist knowledge to scientists in other disciplines. They must equally be able to understand the contributions of other specialists towards their common goal. Drug discovery scientists adapt their scientific activities to the requirements of the project to which they contribute, and are often required to abandon one of their own ideas to contribute to somebody else’s. This is distinctly different from the academic
environment where scientists typically follow their own ideas and their interests, generated usually by the results of their previous research or occasional scientific ‘hot topics’.
However, the interaction between academic and drug discovery sciences is essential. The life sciences (including chemistry) are absolutely central to drug discovery because they are needed to improve the knowledge about disease processes to enable progress in pharmacological (and biological) therapies. The life sciences are currently in an exponential phase of knowledge generation, which occurs primarily in the academic environment; therefore, drug discovery scientists need to have very close and frequent interactions with their colleagues in academia.
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