ISSN: 1758-4272

International Journal of Clinical Rheumatology

Platelet Rich Plasma

Autologous platelet-rich plasma (PRP) is a therapy that includes fibrin and high growth factor concentrations, with the ability to enhance rapid wound healing. PRP is made from animals that have their own (autologous) whole blood. Platelets are extracted and the release of growth factors from platelets is triggered, usually by mixing the platelet concentration with bovine thrombin and calcium.     After infarction and before reperfusion, injecting it into the myocardium significantly increases left ventricular mechanical activity in rabbit hearts during in vivo reperfusion and facilitates angiogenesis and mitogenesis in the core of the sheep when injected 3 weeks after coronary ligation and examined 9 weeks later. In addition to the protein-promoting growth and healing, PRP provides a scaffold that traps cells such as stem cells in the injury area allowing the proteins time to help differentiate the cells into cardiac myocytes. 

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