ISSN: 2048-9145

Pharmaceutical Bioprocessing

Pharmacodynamics Top Journals

Pharmacodynamics places specific stress on dose–response relationships, that is, the relationships between drug concentration and impact. The majority of medicine either   1.       Mimic or inhibit normal physiological/biochemical processes or inhibit pathological processes in animals or 2.       Inhibit very important processes of endo or ectoparasites and microorganism organisms. There are seven main drug actions: ·         Stimulating action through direct receptor agonism and downstream effects ·         Depressing action through direct receptor agonism and downstream effects (ex.: inverse agonist) ·         Blocking/antagonizing action (as with silent antagonists), the drug binds the receptor however doesn't activate it ·         stabilizing action, the drug looks to act neither as a stimulant or as a depressant (ex.: some medication possess receptor activity that permits them to stabilize general receptor activation, like buprenorphine in opioid dependent people or aripiprazole in schizophrenic disorder, all looking on the dose and therefore the recipient) ·         Exchanging/replacing substances or accumulating them to create a reserve (ex.: animal starch storage) ·         Direct helpful reaction as in radical scavenging ·         Direct harmful reaction which could end in injury or destruction of the cells, through induced  toxicant or fatal injury (cytotoxicity or irritation)  

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