ISSN: 2048-9145

Pharmaceutical Bioprocessing

Nanopharmacology

Nanopharmacology is defined as application of  Nanotechnology for the development  and/or  discovery  of  methods  to  deliver  drugs  and   nanomedicines developed to operate on a nanometer size range (typically <500  nm)  with  novel  engineered  properties  that  provide  medical  and 4pharmaceutical benefits, specifically for treatment of diseases,   such drug delivery system is the nanoparticle drug delivery system (NPDDS). Below 100 nm, materials exhibit different, more desirable physical, chemical, and biological properties. Given  the  enormity  and  immediacy of  the  unmet needs of therapeutic areas which can lead to drugs that can extend life and 5save untimely deaths.   Challenges in pharmaceutical industry are poor aqueous  solubility,  tunable  release  profiles,  structural  stability, biocompatibility, and  the  confinement  of therapeutic  action  of  drugs  to diseased sites.   NPDDS has improved   pharmacokinetics of drugs   like solubility due to the increased surface-to-volume ratio of small particles and increased bioavailability due to  protection  against  decrease  in drug effects  due  to excessive  metabolism.    

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