ISSN: 2041-6792

Clinical Investigation

Microbial Proteomics

 Many microbes flourish in our surroundings; however, most of these microbes are invisible to naked eyes. Given their simple cellular structure and less-demanding condition of culture, microorganisms are subjected to extensive researches. Compared with “immense” species like plants and animals, microbes possess relatively tiny genomes, which is more feasible for sequencing. Proteomics is widely utilized in both fundamental and applied research to uncover metabolic mechanisms underlying cellular processes. Proteins embody the biological functions transmitted from genes in most cases. These amazing cellular functions mainly believe elaborate protein interaction networks that can't be elucidated by one protein or a little set of proteins. The potential of proteomics to cope with crucial issues in microbial field is especially hooked in to the sustained development of varied proteomic technologies, which respectively show their talent in proteomic research either qualitatively or/and quantitatively. Proteomic studies systematically provide identification or/and quantitative information on proteins from microorganisms. During this trend, large-scale proteomic technologies emerge and develop prosperously. Proteomic studies provide genome-wide identification or/and quantitative measurement for proteins from microorganisms. Microbial proteomics witnessed the birth of two-dimensional gel electrophoresis technology to separate the proteins of E. coli. The abilities of microorganisms to endure severe environmental stresses, like heat , toxic compounds, or pollutants, and to infect their hosts, are valuable resources in fundamental and applied research.  

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