Journal of Pediatric Neurological Disorders

Leading International Journals In Pediatric Nephrology

The areas discussed are those most relevant to us: the premature infant, the role of growth hormone in bone mass accretion, the child with nutritional disturbances. Some data are old, others new, but the substance is vital and refreshing. What discussion of bone density would be complete without “Bone Analysis by Computer Tomography?” Our volume thus contains a modest amount of information on the subject. This area remains too controversial in pediatric osteology to comment upon in a more definitive manner. Last, the section on “Alternative Methods for Bone Analysis” was not needed at all, and served only to let some out‐dated methods with little external validity persist in the medical literature.The most exciting sections, and that which provided the newest data, were the two on “Biochemical Markers of Collagen‐ and Bone‐Turnover” and “‐as Predictors of Growth.” These pages allow the reader to learn some of the pitfalls and benefits of most of the available serum‐ and urine‐based assays of bone cell activity, in normal children and those with the disorders relevant to pediatric medicine.The last section, “New Therapeutical Approaches,” is rather brief, and focused mostly on bisphosphonates only. It does not represent the large amount of work being performed with many other agents today. However, some new data about the safety and efficacy of bisphosphonates are noted.

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