Journal of Biochemistry Research

Genome Engineeeing Open Access Journals

 Genome editing technologies enable scientists to make changes to DNA, leading to alterations in physical traits, like eye color, and disease risk. Scientists use dissimilar technologies to do this. More in recent times, a new genome editing tool called CRISPR, designed in 2009, has made it cooler than ever to edit DNA. CRISPR is simpler, closer, inexpensive, and more accurate than older genome editing methods. Many scientists who perform genome editing now use CRISPR.These technologies act like scissors, cutting the DNA at a specific spot. Then scientists can eliminate, add, or replace the DNA where it was cut.The first genome editing technologies were established in the late 1900s.   Genome engineering technologies supported artificial nucleases and transcription factors modify the targeted modification of the sequence and expression of genes. These designed nucleases Associate in Nursingd transcription factors generally incorporates a DNA-binding domain connected to an effector module. metal finger proteins (ZFPs) and transcription activator-like effector (TALE) DNA-binding domains were discovered in nature and systems are developed to engineer artificial versions of those proteins with the potential to acknowledge any ester sequence within the ordination. ordination engineering within the previous few years has become additional facile through the utilization of programmable site-specific nucleases like TALENs and Cas9, which may be designed to focus on nearly any DNA sequence. because the use of ZFNs, TALENs, and Cas9 in analysis and clinical settings continues to grow, efforts to reveal comprehensive the DNA cleavage specificity of programmable nucleases can become more and more vital.

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