An abnormal growth of cells that stays within the world during which it started and has not spread into surrounding breast tissue is named a carcinoma in place (CIS) [kar-sin-OE-ma in SY-too]. The term in place means “in place.” CIS is noninvasive because it hasn’t spread to surrounding breast tissue or other areas of the body. Invasive carcinoma is more serious because it can spread to the lymph nodes and to other areas of the body. There are two sorts of CIS: lobular carcinoma in place (LCIS) and ductal carcinoma in place (DCIS). to properly diagnose both LCIS and DCIS, a biopsy (removal of a sample of tissue) must be done. Lobular carcinoma in place (LCIS) develops within the area of the breast where milk is formed (the lobule). the traditional lining of cells of the lobule grows quite usual and fills the whole lobule. LCIS cells stay within the lobule of the breast and infrequently developes into carcinoma . it always can't be diagnosed by a physical exam or mammogram. LCIS is usually found accidentally when a biopsy is completed to diagnose another breast problem or suspicious lump.  

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