Abstract

Regulation of Gene Expression by miR-21

Author(s): Zihadul Hakim

MicroRNA-21 (miR-21) is a small RNA molecule that plays a crucial role in the post-transcriptional regulation of gene expression. It has been extensively studied in various biological contexts, including cancer, cardiovascular disease, and development. This article explores the mechanisms by which miR-21 interacts with its target genes, influences cellular processes, and contributes to disease pathogenesis. Additionally, it discusses the therapeutic potential of modulating miR-21 expression for the treatment of related disorders. MicroRNA-155 (miR-155) is a multifunctional microRNA that has emerged as a key player in cancer biology. This article delves into the intricate roles of miR-155 in promoting or suppressing cancer development, depending on the cellular context and specific target genes. It highlights the regulatory networks involving miR-155 and discusses its potential as a diagnostic biomarker and therapeutic target in various cancer types. The article also explores ongoing research efforts aimed at elucidating the molecular mechanisms underlying miR-155's impact on cancer progression.