Multimodal imaging in AIDS-associated cryptococcal disease

Author(s): Flores Herrera Maria Fernanda

To report multimodal imaging discoveries in two cases of AIDS-related cryptococcal chorioretinitis related with uveitis and vasculitis. Discoveries on clinical examination, color fundus photography, fluorescein and indocyanine green angiographies, and optical coherence tomography. Both patients were analyzed with Cryptococcus neoformans meningitis within the setting of untreated HIV contamination with CD4+ T cell. Visual appearances happened amid the course of the antifungal treatment for meningitis. In both cases, fundus appeared vitritis. Fluorescein angiography permitted the characterization of vasculitis injuries, and indocyanine green angiography shown choroidal association. In combination with optical coherence tomography, ICG and FA permitted the appraisal of treatment reaction. These two cases uncover the potential of C. neoformans to contaminate nearly all visual structures and the basic role of multimodal imaging in standard assessment and within the follow-up of patients.