Evaluation of doppler parameters of ophthalmic artery and central retinal artery in type 2 diabetics using Colour Doppler Imaging

Author(s): Debarpita Datta*, Debashis Dakshit, Nupur Basu & Ruchi Bansal

Objectives: To investigate the doppler parameters of ophthalmic and central retinal artery in type 2 diabetes mellitus patients with Colour Doppler Imaging (CDI) and compare the results with non-diabetic controls.

Materials and methods: This prospective study included 30 type 2 diabetic patients and 15 controls. Diabetic patients were further divided into subjects with no retinopathy (n=15) and subjects with retinopathy (n=15). CDI was performed using GE Logitech P9 ultrasound. The Peak Systolic Velocity (PSV), End-Diastolic Velocity (EDV), Resistivity Index (RI) and Pulsatile Index (PI) of ophthalmic (OA) and Central Retinal Artery (CRA) along with Central Retinal Vein (CRV) were recorded.

Results: RI in the ophthalmic artery was significantly higher in both diabetic groups than the control group (P=0.001,). Diabetics without retinopathy had decreased blood flow velocity (PSV and EDV) in OA compared to controls (P=0.002 and P=0.0011, respectively). Diabetics with retinopathy had significantly reduced EDV and PSV and increased RI in CRA compared to diabetics without retinopathy (P=0.001). Significant correlation was noted among the groups. Pearson’s coefficient analysis analysed that RI of OA has a positive corelation with glycosylated haemoglobin and duration of diabetes.

Conclusion: Significant changes in resistivity index and flow velocities were observed in the ophthalmic artery and central retinal artery in diabetics compared to controls. CDI could be useful to predict individuals at higher risk for developing severe DR.