Abstract

Advancements in Targeted Therapies for Autoimmune Diseases: A Review of Recent Clinical Trials

Author(s): Dr. Joel Wilshon*

Autoimmune diseases (ADs) are a diverse group of disorders where the immune system erroneously attacks the body’s own tissues. Traditionally, treatment for autoimmune diseases has involved non-specific immunosuppressive therapies, which often lead to significant side effects and incomplete disease control. However, recent advancements in targeted therapies have transformed the management of autoimmune diseases by allowing for more precise modulation of immune responses. This review provides an overview of the latest clinical trials investigating targeted therapies for autoimmune diseases, focusing on the development of biologic agents, small molecules, and immune checkpoint inhibitors. We discuss the mechanisms of action, clinical outcomes, and potential challenges associated with these therapies across various autoimmune conditions, including rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), multiple sclerosis (MS), and inflammatory bowel disease (IBD). Furthermore, we explore the promise of personalized medicine and the potential for combination therapies to enhance efficacy and minimize side effects.


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