ISSN: 2048-9145

Pharmaceutical Bioprocessing

Pharmacogenetics Top Journals

 Pharmacogenetics was described as the study of drug response variability due to inheritance. Is the science of understanding how genetic variability affects the outcomes of drug treatment. Pharmacogenetics / Pharmacogenomics is the study of changes in the sequence / characteristics of DNA and RNA as relating to drug reaction and toxicity. Pharmacogeneticsor Pharmacogenomics (PG) describes the study in treated patients of human genetic factors that influence drug toxicity or reaction. Given human genetic or genomic information for disease risk prediction, optimizing therapeutic agents or dosing schemes, medication toxicity predictions and cancer growth responses. While the terms pharmacogenetics and pharmacogenomics are often used interchangeably, pharmacogenetics generally refers to the effects of a single genetic marker while pharmacogenomics is broader in context, referring to the collective influence of genome-wide variability for modulating the drug response profile of an individual. Pharmacogenetics can affect both the pharmacokinetics and drug pharmacodynamics. This variability has relevance for dosing, sensitivity to therapy, likelihood of side-effects.

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