Journal of Leukaemia & Lymphoma Research

Pemphigus Vulgaris Scientific Journals

Pemphigus vulgaris is a rare autoimmune disease that causes the skin and mucous membranes to blister painfully. If you have an autoimmune disease, your immune system attacks your healthy tissues in the wrong way. The most common type of a group of autoimmune disorders called pemphigus is pemphigus vulgaris. Each pemphigus type is characterized by the place where the blisters form. This disease usually begins in the mouth with blisters, and then on the skin. The blisters sometimes impact the genital membranes. Pemphigus vulgaris is potentially dangerous. Treatment is vital, and usually involves the use of corticosteroids to suppress the immune system. If it is not treated the condition can cause serious complications. Some of these complications can have fatal consequences. Before corticosteroids were introduced in the 1950s, the death rate from this disease averaged 75 per cent. With today's treatments, that improved dramatically.

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