Annals of Clinical Trials and Vaccines Research

Oncolytic Virus Open Access Journals

      Oncolytic viruses are a sort of immunotherapy that uses viruses to infect and destroy cancer cells.   Viruses are particles that infect or enter our cells and then use the cell’s genetic machinery to make copies of themselves and subsequently spread to surrounding uninfected cells. Infection by certain viruses has been implicated within the development of certain cancers, like the hepatitis B virus (HBV) in cancer of the liver and therefore the human papilloma virus (HPV) in cervical cancer and head and also in neck cancer. (In the case of HPV and hepatitis, another sort of immunotherapy—cancer vaccines—has shown the power to stop infection and protect against the formation of those HPV- and HBV-related cancers). Side effects may vary according to the type of oncolytic virus—and what exactly it targets—and may also be influenced by the location and type of cancer as well as a patient’s overall health. Due to their potential to infect healthy cells also such as it stimulate overall immune activity, sometimes oncolytic viruses may cause the system to attack healthy cells, and their use may carry some risk of infection. Patients should consult their doctors and therefore the remainder of their care team to realize a far better and fuller understanding of the potential risks and side effects related to specific oncolytic viruses.

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