HIV Genotype Testing
HIV Drug Resistance Testing is used to determine whether an HIV patient has a mutated form of the virus not responding to
antiretroviral therapy ( ART). Testing of genotypical resistance examines the genetic structure (genotype) of HIV in a patient. The patient receives a blood sample, and the HIV is analyzed for the presence of specific genetic
mutations known to cause resistance to specific drugs. Researchers have determined, for example, that lamivudine (Epivir ®) and emtricitabine (Emtriva ®) are not effective against forms of HIV that contain the "M184V" mutation in its reverse transcriptase gene. If a patient tests positive for this mutation, it is highly likely that he or she will be resistant to both drugs, and prescribing different medicines.
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