HIV Diagnosis Open Access Journals

Tests for HIV differ in methodology as well as testing purpose. Generally, tests are done for three reasons: individual diagnosis, protection of blood or tissue products safety, and public health surveillance. According to the objective of testing, the most appropriate test is chosen based on convenience, test characteristics, and the population to whom the testing subject belongs. Presence of antibody to HIV proteins is now well accepted as indicative of HIV infection except in extenuating circumstances such as after receiving an experimental vaccine. Certain clinical conditions may also rarely result in false-positive HIV antibody tests. Over the years, experience with the serologic tests and knowledge of viral subtypes helped refine testing algorithms that have high sensitivity and specificity for the purpose of clinical diagnosis. In general, a highly sensitive test is used for screening, followed by a highly specific test for confirmation.  

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