JBR Journal of Interdisciplinary Medicine and Dental Sciences

Hereditary Spastic Paraplegia Top Journals

 Hereditary spastic paraplegia (HSP) may be a group of hereditary, degenerative, neurological disorders that primarily affect the upper motor neurons. Upper motor neurons within the brain and medulla spinalis deliver signals to the lower motor neurons, which successively, carry messages to the muscles. As degeneration continues, symptoms worsen. If only the lower body is affected, HSP is classified as uncomplicated or pure. HSP is assessed as complicated or complex if other systems are involved. In these cases, additional symptoms, including impaired vision, ataxia, epilepsy, cognitive impairment, peripheral neuropathy, and/or deafness, occur. the various sorts of HSP are caused by mutations in several genes. Inheritance varies. There are not any specific treatments to stop, slow, or reverse HSP. Individual symptoms may be treated with medications and/or physical therapy.   Patients and consumers with specific questions on a genetic test should contact a health care provider or genetics professional.  Treatment is symptomatic and supportive. Medications could also be considered for spasticity and urinary urgency. Regular physiotherapy is vital for muscle strength and to preserve range of motion. Upper motor neurons within the brain and medulla spinalis deliver signals to the lower motor neurons, which successively, carry messages to the muscles. As degeneration continues, symptoms worsen.

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