Annals of Clinical Trials and Vaccines Research

Hepatitis B Infection

Hepatitis B virus (HBV) infection is an important public health problem in Canada. In keeping with evolving evidence and understanding of HBV pathogenesis, the Canadian Association for the Study of Liver Disease periodically publishes HBV management guidelines. The goals of the 2018 guidelines are to highlight the public health impact of HBV infection in Canada and the need to improve diagnosis and linkage to care, recommend current best-practice guidelines for treatment of HBV, summarize the key HBV laboratory diagnostic tests, and review evidence on HBV management in special patient populations and include more detail on management of HBV in pediatric populations. An overview of novel HBV tests and therapies for HBV in development is provided to highlight the recent advances in HBV clinical research. The aim and scope of these guidelines are to serve as an up-to-date, comprehensive resource for Canadian health care providers in the management of HBV infection. Hepatitis B virus (HBV) infection is an important public health problem in Canada. In keeping with evolving evidence and understanding of HBV pathogenesis, the Canadian Association for the Study of the Liver (CASL) has periodically published HBV management guidelines. In 2017, a proposal was brought forward by the HBV Guidelines panel co-chairs (CS Coffin and SK Fung) and a committee member (MM Ma) to the CASL Education Committee to update the 2012 Canadian HBV guidelines. Members of the writing committee panel were recommended by the co-chairs and approved by the chair of the CASL education and the CASL guidelines committees.  

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