Journal of Biochemistry Research

Frequency-dependent Selection Online Journals

    Frequency-dependent choice happens once the fitness of a genotype depends on its frequency. It’s potential for the fitness of a genotype to increase (positively frequency-dependent) or decrease (negatively frequency-dependent) as a result of the genotype frequency among the population will increase. Frequency-dependent choice is outlined as a scenario wherever fitness depends upon the frequency of a makeup or genotype throughout a population. Our focus here is on negative frequency-dependent choice, whereby fitness of a makeup or genotype will increase as its frequency throughout a population decreases. Negative frequency-dependent choice is believed to be a primary driver of coevolution between biological antagonists. The idea that choice pro rare genotypes or phenotypes may drive antagonistic coevolution began with J. B. S. Haldane (1949). In 1949, biologists were simply setting out to discover that plenty of species featured astonishingly high levels of genetic variation for ‘resistance’ to varied diseases – diversity that got to quickly be lost if just one or a couple of phenotypes or genotypes systematically given resistance. Haldane (1949) recommended that the maintenance of this diversity can be explained by a scenario wherever parasites disproportionately attack common host varieties – simply because the parasites have tailored to take advantage of a standard host resource. Here, a mutation that given a rare ‘biochemical makeup’ (Haldane’s words) might confer parasite resistance as a result of parasites haven't nonetheless had an opportunity to adapt to this rare phenotype.    

High Impact List of Articles

Relevant Topics in Medical