Esophago-Gastric Junction

The oesophagogastric junction may be a muscle, not a mucosal, junction. The boundary of the esophagus is at the upper esophageal sphincter and lower esophageal sphincter (LES) at the oral and anal ends, respectively. The distal end of the LES is that the oesophagogastric junction. Fine palisade vessels occur within the mucosa above the LES, and therefore the oesophagogastric junction is at the distal end of this palisade zone. The oesophagogastric junction is defined because the part becoming the lumen seen in radiographic, examination or in surgically resected specimens. It's extremely difficult to spot the oesophagogastric junction pathologically, requiring special effort. A 47-year-old man was found to possess a kind 2 tumor of the oesophagogastric junction on upper gastrointestinal endoscopy. Biopsy specimens revealed epithelial cell carcinoma of the esophagus and adenocarcinoma of the stomach. The preoperative diagnosis was a collision carcinoma. No distant metastases were identified on computed tomography; therefore, partial esophagectomy and gastrectomy were performed. Pathological examination of the resected specimen revealed adenosquamous carcinoma at the oesophagogastric junction (TNM classification: stage IIA, T3N0M0). Adenosquamous cell carcinoma of the esophagus and stomach is rare, but that at the oesophagogastric junction even rarer. This study is to know the clinic pathological manifestations, treatment, and prognostic factors of adenosquamous carcinoma (ASC) of the esophagus and oesophagogastric junction , a rare malignancy.    

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