Journal of Medicinal and Organic Chemistry

Epitope

 An epitope, conjointly referred to as matter determinant, is that the part of Associate in Nursing matter that's recognized by the system, specifically by antibodies, B cells, or T cells. as an example, the epitope is that the specific piece of the matter to that Associate in Nursing protein binds Epitope, conjointly known as matter determinant, portion of a far off macromolecule, or antigen, that's capable of stimulating Associate in Nursing response. Associate in nursing epitope is that the part of the matter that binds to a selected matter receptor on the surface of a B cell. Every of those antibodies binds to a selected epitope situated on it macromolecule. Binding between the protein and also the epitope happens at the matter Binding website that is named a paratope and is found at the tip of the variable region on the protein. Every matter generally has several epitopes. as an example, insulin, a dimeric macromolecule with fifty one amino acids, has on its surface a minimum of a hundred and fifteen protein epitopes (Schroer et al. 1983).  

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