Annals of Clinical Trials and Vaccines Research

Comparitive Genome Hybridization Impact Factor

 Comparative genomic hybridization is a molecular cytogenetic method for analyzing copy number variations with respect to the level of ploidy in a test sample's DNA compared to a reference sample, without the need for tumor cells. The purpose of this technique is to quickly and efficiently compare two genomic DNA samples that originate from two sources, which are often closely related, because they are believed to have differences in gain or loss of whole chromosomes or subchromosome regions. This technique was originally developed to evaluate the differences between solid and normal tissue chromosomal integrity, and has an improved resolution of 5-10 megabytes compared to the more traditional cytogenetic stripping technique and on-site fluorescence disorder limited by the microscope resolution.    

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