Breast Carcinogenesis Innovations

A cancer which forms in breast cells. Breast cancer can happen in women and rarely in men. Breast cancer signs include a lump in the breast, bloody discharge from the nipple and changes in nipple or breast form or texture. Its treatment is based on cancer level. Chemotherapy, chemotherapy , hormone therapy, and surgery can be used. There are potential variations between carcinogenesis in the male and female breast. Mutations in the genes of BRCA1 and BRCA2 cause hereditary breast and ovarian cancer syndrome, but male cancer risk is lower. Risk factors for men to develop breast cancer are low androgen and heavy exposure to estrogen, which is inherent in male-to - female hormone treatment. Breast cancer has been examined in transsexual subjects. Three cases of very rare tumors of the breast are not considered as sensitive to estrogen. While there has been a considerable rise in the number of transsexual individuals undergoing sex reassignment, there is a significant lack of breast cancer in male to female individuals. The impression is given that in male to female individuals breast cancer follows patterns of male breast cancer. Estrogens have a significant effect on breast cell proliferation and the target cell population, the TEB cells. Estrogen appears to be a significant influence in breast carcinogenesis, but it is probably just one of a hormone balance that affects the differentiation and proliferation of the target cell population. 

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