Journal of Leukaemia & Lymphoma Research

Bone Marrow Workshop

 Bone marrow examination refers to the pathologic analysis of samples of bone marrow obtained by bone marrow diagnostic test (often referred to as trephine biopsy) and bone marrow aspiration. Bone marrow examination is employed within the designation of variety of conditions, as well as cancer of the blood, myeloma, lymphoma, anemia, and cytopenia. The bone marrow produces the cellular components of the blood, as well as platelets, red blood cells and white blood cells. whereas abundant info are often gleaned by testing the blood itself (drawn from a vein by phlebotomy), it's generally necessary to look at the supply of the blood cells within the bone marrow to get a lot of info on hematopoiesis; this is often the role of bone marrow aspiration and diagnostic test.   Bone marrow samples are often obtained by aspiration and trephine diagnostic test. Sometimes, a bone marrow examination can embrace each an aspirate and a diagnostic test. The aspirate yields semi-liquid bone marrow, which may be examined by a diagnostician underneath a lightweight magnifier and analyzed by flow cytometry, body analysis, or enzyme chain reaction (PCR). Frequently, a trephine diagnostic test is additionally obtained, that yields a slim, cylindrically formed solid piece of bone marrow, two millimeter wide and a pair of cm long (80 μL), that is examined microscopically (sometimes with the help of immunohistochemistry) for physiological condition and infiltrative processes.

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